Fpr1, a primary target of rapamycin, functions as a transcription factor for ribosomal protein genes cooperatively with Hmo1 in Saccharomyces cerevisiae

Fpr1 (FK506-sensitive proline rotamase 1), a protein of the FKBP12 (FK506-binding protein 12 kDa) family in Saccharomyces cerevisiae, is a primary target for the immunosuppressive agents FK506 and rapamycin. Fpr1 inhibits calcineurin and TORC1 (target of rapamycin complex 1) when bound to FK506 and...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Kasahara, Koji, Nakayama, Risa, Shiwa, Yuh, Kanesaki, Yu, Ishige, Taichiro, Yoshikawa, Hirofumi, Kokubo, Tetsuro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357790/
https://ncbi.nlm.nih.gov/pubmed/32603360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008865
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