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Whole-Genome Profiling of a Novel Mutagenesis Technique Using Proofreading-Deficient DNA Polymerase δ

A novel mutagenesis technique using error-prone DNA polymerase δ (polδ), the disparity mutagenesis model of evolution, has been successfully employed to generate novel microorganism strains with desired traits. However, little else is known about the spectra of mutagenic effects caused by disparity...

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Detalhes bibliográficos
Main Authors: Shiwa, Yuh, Fukushima-Tanaka, Sanae, Kasahara, Ken, Horiuchi, Takayuki, Yoshikawa, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364565/
https://ncbi.nlm.nih.gov/pubmed/22675654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/860797
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