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Whole-Genome Profiling of a Novel Mutagenesis Technique Using Proofreading-Deficient DNA Polymerase δ

A novel mutagenesis technique using error-prone DNA polymerase δ (polδ), the disparity mutagenesis model of evolution, has been successfully employed to generate novel microorganism strains with desired traits. However, little else is known about the spectra of mutagenic effects caused by disparity...

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Bibliografische gegevens
Hoofdauteurs: Shiwa, Yuh, Fukushima-Tanaka, Sanae, Kasahara, Ken, Horiuchi, Takayuki, Yoshikawa, Hirofumi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364565/
https://ncbi.nlm.nih.gov/pubmed/22675654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/860797
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