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Mutation tendency of mutator Plasmodium berghei with proofreading-deficient DNA polymerase δ
In this study, we investigated the mutation tendency of a mutator rodent malaria parasite, Plasmodium berghei, with proofreading-deficient DNA polymerase δ. Wild-type and mutator parasites were maintained in mice for over 24 weeks, and the genome-wide accumulated mutations were determined by high-th...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5109483/ https://ncbi.nlm.nih.gov/pubmed/27845384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36971 |
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