Generation of Rodent Malaria Parasites with a High Mutation Rate by Destructing Proofreading Activity of DNA Polymerase δ

Plasmodium falciparum malaria imposes a serious public health concern throughout the tropics. Although genetic tools are principally important to fully investigate malaria parasites, currently available forward and reverse tools are fairly limited. It is expected that parasites with a high mutation...

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Detalhes bibliográficos
Main Authors: Honma, Hajime, Hirai, Makoto, Nakamura, Shota, Hakimi, Hassan, Kawazu, Shin-ichiro, Palacpac, Nirianne M.Q., Hisaeda, Hajime, Matsuoka, Hiroyuki, Kawai, Satoru, Endo, Hiroyoshi, Yasunaga, Teruo, Ohashi, Jun, Mita, Toshihiro, Horii, Toshihiro, Furusawa, Mitsuru, Tanabe, Kazuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131837/
https://ncbi.nlm.nih.gov/pubmed/24670267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dsu009
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