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Ablation of the leptin receptor in myeloid cells impairs pulmonary clearance of Streptococcus pneumoniae and alveolar macrophage bactericidal function
Leptin is a pleiotropic hormone produced by white adipose tissue that regulates appetite and many physiological functions, including the immune response to infection. Genetic leptin deficiency in humans and mice impairs host defenses against respiratory tract infections. Since leptin deficiency is a...
Tallennettuna:
| Julkaisussa: | Am J Physiol Lung Cell Mol Physiol |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Physiological Society
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6087898/ https://ncbi.nlm.nih.gov/pubmed/29565180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00447.2017 |
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