Glucocorticoid-augmented efferocytosis inhibits pulmonary pneumococcal clearance in mice by reducing alveolar macrophage bactericidal function

Inhaled corticosteroid(s) (ICS) increase community-acquired pneumonia (CAP) incidence in patients with chronic obstructive pulmonary disease (COPD) by unknown mechanisms. Apoptosis is increased in the lungs of COPD patients. Uptake of apoptotic cells (AC) (“efferocytosis”) by alveolar macrophages (A...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Stolberg, Valerie R., McCubbrey, Alexandra L., Freeman, Christine M., Brown, Jeanette P., Crudgington, Sean W., Taitano, Sophina H., Saxton, Bridget L., Mancuso, Peter, Curtis, Jeffrey L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475455/
https://ncbi.nlm.nih.gov/pubmed/25987742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402217
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