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Regulation of fluid reabsorption in rat or mouse proximal renal tubules by asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase 1

Nitric oxide prevents hypertension yet enhances proximal tubule Na(+) reabsorption. Nitric oxide synthase is inhibited by asymmetric dimethylarginine (ADMA) that is metabolized by dimethylarginine dimethylaminohydrolase (DDAH) whose type 1 isoform is expressed abundantly in the proximal tubule (PT)....

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Pubblicato in:Am J Physiol Renal Physiol
Autori principali: Bell, Tracy, Araujo, Magali, Luo, Zaiming, Tomlinson, James, Leiper, James, Welch, William J., Wilcox, Christopher S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087787/
https://ncbi.nlm.nih.gov/pubmed/29513072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00560.2017
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