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α-Ketoglutarate stimulates pendrin-dependent Cl(−) absorption in the mouse CCD through protein kinase C
α-Ketoglutarate (α-KG) is a citric acid cycle intermediate and a glutamine catabolism product. It is also the natural ligand of 2-oxoglutarate receptor 1 (OXGR1), a G(q) protein-coupled receptor expressed on the apical membrane of intercalated cells. In the cortical collecting duct (CCD), Cl(−)/ [Fo...
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| 發表在: | Am J Physiol Renal Physiol |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6087786/ https://ncbi.nlm.nih.gov/pubmed/29412702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00576.2017 |
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