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Drug resistance profiles of mutations in the RET kinase domain
BACKGROUND AND PURPOSE: Alterations in the tyrosine kinase enzyme RET are found in thyroid and lung cancer. While RET TK inhibitors (TKIs) are used to treat thyroid cancer and are in clinical trials for RET fusion‐positive non‐small cell lung cancer, the impact of mutations in the RET kinase domain...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6086982/ https://ncbi.nlm.nih.gov/pubmed/29908090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14395 |
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