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Single cell analysis reveals a biophysical aspect of collective cell-state transition in embryonic stem cell differentiation

In the stem cell research field, the molecular regulatory network used to define cellular states has been extensively studied, however, the general driving force guiding the collective state dynamics remains to be identified from biophysical aspects. Here we monitored the time-development of the cel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Okamoto, Kazuko, Germond, Arno, Fujita, Hideaki, Furusawa, Chikara, Okada, Yasushi, Watanabe, Tomonobu M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086879/
https://ncbi.nlm.nih.gov/pubmed/30097661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30461-2
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