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Efficient analysis of mammalian polysomes in cells and tissues using Ribo Mega-SEC

We describe Ribo Mega-SEC, a powerful approach for the separation and biochemical analysis of mammalian polysomes and ribosomal subunits using Size Exclusion Chromatography and uHPLC. Using extracts from either cells, or tissues, polysomes can be separated within 15 min from sample injection to frac...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Yoshikawa, Harunori, Larance, Mark, Harney, Dylan J, Sundaramoorthy, Ramasubramanian, Ly, Tony, Owen-Hughes, Tom, Lamond, Angus I
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086667/
https://ncbi.nlm.nih.gov/pubmed/30095066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36530
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