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Global Subcellular Characterization of Protein Degradation Using Quantitative Proteomics

Protein degradation provides an important regulatory mechanism used to control cell cycle progression and many other cellular pathways. To comprehensively analyze the spatial control of protein degradation in U2OS osteosarcoma cells, we have combined drug treatment and SILAC-based quantitative mass...

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Autores principales: Larance, Mark, Ahmad, Yasmeen, Kirkwood, Kathryn J., Ly, Tony, Lamond, Angus I.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591657/
https://ncbi.nlm.nih.gov/pubmed/23242552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.024547
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