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Global Subcellular Characterization of Protein Degradation Using Quantitative Proteomics

Protein degradation provides an important regulatory mechanism used to control cell cycle progression and many other cellular pathways. To comprehensively analyze the spatial control of protein degradation in U2OS osteosarcoma cells, we have combined drug treatment and SILAC-based quantitative mass...

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Détails bibliographiques
Auteurs principaux: Larance, Mark, Ahmad, Yasmeen, Kirkwood, Kathryn J., Ly, Tony, Lamond, Angus I.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591657/
https://ncbi.nlm.nih.gov/pubmed/23242552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.024547
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