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Global Subcellular Characterization of Protein Degradation Using Quantitative Proteomics
Protein degradation provides an important regulatory mechanism used to control cell cycle progression and many other cellular pathways. To comprehensively analyze the spatial control of protein degradation in U2OS osteosarcoma cells, we have combined drug treatment and SILAC-based quantitative mass...
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Hauptverfasser: | , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
The American Society for Biochemistry and Molecular Biology
2013
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3591657/ https://ncbi.nlm.nih.gov/pubmed/23242552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.024547 |
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