Systematic Analysis of Protein Pools, Isoforms, and Modifications Affecting Turnover and Subcellular Localization

In higher eukaryotes many genes encode protein isoforms whose properties and biological roles are often poorly characterized. Here we describe systematic approaches for detection of either distinct isoforms, or separate pools of the same isoform, with differential biological properties. Using inform...

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Библиографические подробности
Главные авторы: Ahmad, Yasmeen, Boisvert, Francois-Michel, Lundberg, Emma, Uhlen, Mathias, Lamond, Angus I.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Biochemistry and Molecular Biology 2012
Предметы:
Special Issue: Prospects in Space and Time
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316725/
https://ncbi.nlm.nih.gov/pubmed/22002106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.013680
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