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Systematic Analysis of Protein Pools, Isoforms, and Modifications Affecting Turnover and Subcellular Localization

In higher eukaryotes many genes encode protein isoforms whose properties and biological roles are often poorly characterized. Here we describe systematic approaches for detection of either distinct isoforms, or separate pools of the same isoform, with differential biological properties. Using inform...

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Main Authors: Ahmad, Yasmeen, Boisvert, Francois-Michel, Lundberg, Emma, Uhlen, Mathias, Lamond, Angus I.
格式: Artigo
語言:Inglês
出版: The American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316725/
https://ncbi.nlm.nih.gov/pubmed/22002106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.013680
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