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Yorkie functions at the cell cortex to promote myosin activation in a non-transcriptional manner

The Hippo signaling pathway is an evolutionarily conserved mechanism that controls organ size in animals. Yorkie is well known as a transcriptional co-activator that functions downstream of the Hippo pathway to positively regulate transcription of genes that promote tissue growth. Recent studies hav...

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Dettagli Bibliografici
Pubblicato in:Dev Cell
Autori principali: Xu, Jiajie, Vanderzalm, Pamela J., Ludwig, Michael, Su, Ting, Tokamov, Sherzod A., Fehon, Richard G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086586/
https://ncbi.nlm.nih.gov/pubmed/30032991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.06.017
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