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RADX modulates RAD51 activity to control replication fork protection
RAD51 promotes homologous recombination repair (HR) of double-strand breaks and acts during DNA replication to facilitate fork reversal and protect nascent DNA strands from nuclease digestion. Several additional HR proteins regulate fork protection by promoting RAD51 filament formation. Here we show...
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| Veröffentlicht in: | Cell Rep |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6086571/ https://ncbi.nlm.nih.gov/pubmed/30021152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.061 |
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