Nrf2 expression and function, but not MT expression, is indispensable for sulforaphane-mediated protection against intermittent hypoxia-induced cardiomyopathy in mice

We reported previously that nuclear factor erythroid 2-related factor 2 (Nrf2) and metallothionein (MT) play critical roles in preventing intermittent hypoxia (IH)-induced cardiomyopathy. In addition, positive feedback regulation between Nrf2 and MT is required for the efficient compensative respons...

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Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Zhou, Shanshan, Wang, Jiqun, Yin, Xia, Xin, Ying, Zhang, Zhiguo, Cui, Taixing, Cai, Jun, Zheng, Yang, Liu, Quan, Cai, Lu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086220/
https://ncbi.nlm.nih.gov/pubmed/30096613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.07.014
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