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High genetic carrier frequency of Wilson’s disease in France: discrepancies with clinical prevalence

BACKGROUND: Wilson’s disease (WD) is a rare autosomal recessive metabolic disease caused by ATP7B gene mutations tat cause excessively high copper levels, particularly in the liver and brain. The WD phenotype varies in terms of its clinical presentation and intensity. Diagnosing this metabolic disor...

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Bibliografische gegevens
Gepubliceerd in:BMC Med Genet
Hoofdauteurs: Collet, Corinne, Laplanche, Jean-Louis, Page, Justine, Morel, Hélène, Woimant, France, Poujois, Aurélia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086069/
https://ncbi.nlm.nih.gov/pubmed/30097039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-018-0660-3
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