Mismatch repair gene mutations lead to lynch syndrome colorectal cancer in rhesus macaques

Colorectal cancer accounts for a substantial number of deaths each year worldwide. Lynch Syndrome is a genetic form of colorectal cancer (CRC) caused by inherited mutations in DNA mismatch repair (MMR) genes. Although researchers have developed mouse models of Lynch Syndrome through targeted mutagen...

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Foilsithe in:Genes Cancer
Main Authors: Dray, Beth K., Raveendran, Muthuswamy, Harris, R. Alan, Benavides, Fernando, Gray, Stanton B., Perez, Carlos J., McArthur, Mark J., Williams, Lawrence E., Baze, Wallace B., Doddapaneni, Harsha, Muzny, Donna M., Abee, Christian R., Rogers, Jeffrey
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2018
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086002/
https://ncbi.nlm.nih.gov/pubmed/30108684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.170
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