Paternal age in rhesus macaques is positively associated with germline mutation accumulation but not with measures of offspring sociability

Mutation is the ultimate source of all genetic novelty and the cause of heritable genetic disorders. Mutational burden has been linked to complex disease, including neurodevelopmental disorders such as schizophrenia and autism. The rate of mutation is a fundamental genomic parameter and direct estim...

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Dettagli Bibliografici
Pubblicato in:Genome Res
Autori principali: Wang, Richard J., Thomas, Gregg W.C., Raveendran, Muthuswamy, Harris, R. Alan, Doddapaneni, Harshavardhan, Muzny, Donna M., Capitanio, John P., Radivojac, Predrag, Rogers, Jeffrey, Hahn, Matthew W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370888/
https://ncbi.nlm.nih.gov/pubmed/32461224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.255174.119
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