Paternal age in rhesus macaques is positively associated with germline mutation accumulation but not with measures of offspring sociability

Mutation is the ultimate source of all genetic novelty and the cause of heritable genetic disorders. Mutational burden has been linked to complex disease, including neurodevelopmental disorders such as schizophrenia and autism. The rate of mutation is a fundamental genomic parameter and direct estim...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Wang, Richard J., Thomas, Gregg W.C., Raveendran, Muthuswamy, Harris, R. Alan, Doddapaneni, Harshavardhan, Muzny, Donna M., Capitanio, John P., Radivojac, Predrag, Rogers, Jeffrey, Hahn, Matthew W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370888/
https://ncbi.nlm.nih.gov/pubmed/32461224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.255174.119
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