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Paternal age in rhesus macaques is positively associated with germline mutation accumulation but not with measures of offspring sociability

Mutation is the ultimate source of all genetic novelty and the cause of heritable genetic disorders. Mutational burden has been linked to complex disease, including neurodevelopmental disorders such as schizophrenia and autism. The rate of mutation is a fundamental genomic parameter and direct estim...

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發表在:Genome Res
Main Authors: Wang, Richard J., Thomas, Gregg W.C., Raveendran, Muthuswamy, Harris, R. Alan, Doddapaneni, Harshavardhan, Muzny, Donna M., Capitanio, John P., Radivojac, Predrag, Rogers, Jeffrey, Hahn, Matthew W.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370888/
https://ncbi.nlm.nih.gov/pubmed/32461224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.255174.119
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