Mismatch repair gene mutations lead to lynch syndrome colorectal cancer in rhesus macaques

Colorectal cancer accounts for a substantial number of deaths each year worldwide. Lynch Syndrome is a genetic form of colorectal cancer (CRC) caused by inherited mutations in DNA mismatch repair (MMR) genes. Although researchers have developed mouse models of Lynch Syndrome through targeted mutagen...

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Detalhes bibliográficos
Publicado no:Genes Cancer
Main Authors: Dray, Beth K., Raveendran, Muthuswamy, Harris, R. Alan, Benavides, Fernando, Gray, Stanton B., Perez, Carlos J., McArthur, Mark J., Williams, Lawrence E., Baze, Wallace B., Doddapaneni, Harsha, Muzny, Donna M., Abee, Christian R., Rogers, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086002/
https://ncbi.nlm.nih.gov/pubmed/30108684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.170
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