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Exploring the biological functional mechanism of the HMGB1/TLR4/MD-2 complex by surface plasmon resonance

BACKGROUND: High Mobility Group Box 1 (HMGB1) was first identified as a nonhistone chromatin-binding protein that functions as a pro-inflammatory cytokine and a Damage-Associated Molecular Pattern molecule when released from necrotic cells or activated leukocytes. HMGB1 consists of two structurally...

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Bibliografische gegevens
Gepubliceerd in:Mol Med
Hoofdauteurs: He, Mingzhu, Bianchi, Marco E., Coleman, Tom R., Tracey, Kevin J., Al-Abed, Yousef
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085627/
https://ncbi.nlm.nih.gov/pubmed/30134799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0023-8
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