Folic acid derived-P5779 mimetics regulate DAMP-mediated inflammation through disruption of HMGB1:TLR4:MD-2 axes

High mobility group box 1 (HMGB1) is a damage-associated molecular pattern (DAMP) protein that mediates inflammatory responses after infection or injury. Previously, we reported a peptide inhibitor of HMGB1 (P5779) that acts by directly interrupting HMGB1/MD-2 binding. Here, fingerprint similarity s...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Sun, Shan, He, Mingzhu, Wang, Yongjun, Yang, Huan, Al-Abed, Yousef
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814057/
https://ncbi.nlm.nih.gov/pubmed/29447234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193028
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