Induction and Amelioration of Methotrexate-Induced Gastrointestinal Toxicity are Related to Immune Response and Gut Microbiota

As a widely used anticancer and immunosuppressive agent, methotrexate (MTX) can induce multiple adverse drug reactions (ADRs), such as gastrointestinal toxicity, the mechanisms are poorly understood. Gut microbiota has been widely reported to be associated with the onset of multiple diseases as well...

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Bibliografski detalji
Izdano u:EBioMedicine
Glavni autori: Zhou, Bailing, Xia, Xuyang, Wang, Peiqi, Chen, Shuang, Yu, Chaoheng, Huang, Rong, Zhang, Rui, Wang, Yantai, Lu, Lian, Yuan, Fengjiao, Tian, Yaomei, Fan, Yingzi, Zhang, Xueyan, Shu, Yang, Zhang, Shouyue, Bai, Ding, Wu, Lei, Xu, Heng, Yang, Li
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2018
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085585/
https://ncbi.nlm.nih.gov/pubmed/30049384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.06.029
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