Induction and Amelioration of Methotrexate-Induced Gastrointestinal Toxicity are Related to Immune Response and Gut Microbiota

As a widely used anticancer and immunosuppressive agent, methotrexate (MTX) can induce multiple adverse drug reactions (ADRs), such as gastrointestinal toxicity, the mechanisms are poorly understood. Gut microbiota has been widely reported to be associated with the onset of multiple diseases as well...

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Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Zhou, Bailing, Xia, Xuyang, Wang, Peiqi, Chen, Shuang, Yu, Chaoheng, Huang, Rong, Zhang, Rui, Wang, Yantai, Lu, Lian, Yuan, Fengjiao, Tian, Yaomei, Fan, Yingzi, Zhang, Xueyan, Shu, Yang, Zhang, Shouyue, Bai, Ding, Wu, Lei, Xu, Heng, Yang, Li
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085585/
https://ncbi.nlm.nih.gov/pubmed/30049384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.06.029
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