Induction and Amelioration of Methotrexate-Induced Gastrointestinal Toxicity are Related to Immune Response and Gut Microbiota

As a widely used anticancer and immunosuppressive agent, methotrexate (MTX) can induce multiple adverse drug reactions (ADRs), such as gastrointestinal toxicity, the mechanisms are poorly understood. Gut microbiota has been widely reported to be associated with the onset of multiple diseases as well...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Autores principales: Zhou, Bailing, Xia, Xuyang, Wang, Peiqi, Chen, Shuang, Yu, Chaoheng, Huang, Rong, Zhang, Rui, Wang, Yantai, Lu, Lian, Yuan, Fengjiao, Tian, Yaomei, Fan, Yingzi, Zhang, Xueyan, Shu, Yang, Zhang, Shouyue, Bai, Ding, Wu, Lei, Xu, Heng, Yang, Li
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085585/
https://ncbi.nlm.nih.gov/pubmed/30049384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.06.029
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