Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery

The lack of engineering systems able to faithfully reproduce complex kidney structures in vitro has made it difficult to efficiently model kidney diseases and development. Using polydimethylsiloxane (PDMS) scaffolds and a kidney-derived cell line we developed a system to rapidly engineer custom-made...

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Vydáno v:EBioMedicine
Hlavní autoři: Benedetti, Valentina, Brizi, Valerio, Guida, Patrizia, Tomasoni, Susanna, Ciampi, Osele, Angeli, Elena, Valbusa, Ugo, Benigni, Ariela, Remuzzi, Giuseppe, Xinaris, Christodoulos
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085557/
https://ncbi.nlm.nih.gov/pubmed/30049385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.06.005
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