Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery

The lack of engineering systems able to faithfully reproduce complex kidney structures in vitro has made it difficult to efficiently model kidney diseases and development. Using polydimethylsiloxane (PDMS) scaffolds and a kidney-derived cell line we developed a system to rapidly engineer custom-made...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Benedetti, Valentina, Brizi, Valerio, Guida, Patrizia, Tomasoni, Susanna, Ciampi, Osele, Angeli, Elena, Valbusa, Ugo, Benigni, Ariela, Remuzzi, Giuseppe, Xinaris, Christodoulos
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085557/
https://ncbi.nlm.nih.gov/pubmed/30049385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.06.005
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