Retrotransposition of a yeast group II intron occurs by reverse splicing directly into ectopic DNA sites

Group II introns, the presumed ancestors of nuclear pre-mRNA introns, are site-specific retroelements. In addition to “homing” to unoccupied sites in intronless alleles, group II introns transpose at low frequency to ectopic sites that resemble the normal homing site. Two general mechanisms have bee...

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Bibliografiska uppgifter
Huvudupphovsmän: Dickson, Lorna, Huang, Hon-Ren, Liu, Lu, Matsuura, Manabu, Lambowitz, Alan M., Perlman, Philip S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2001
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC60849/
https://ncbi.nlm.nih.gov/pubmed/11687644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231494498
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