Retrotransposition of a yeast group II intron occurs by reverse splicing directly into ectopic DNA sites

Group II introns, the presumed ancestors of nuclear pre-mRNA introns, are site-specific retroelements. In addition to “homing” to unoccupied sites in intronless alleles, group II introns transpose at low frequency to ectopic sites that resemble the normal homing site. Two general mechanisms have bee...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Dickson, Lorna, Huang, Hon-Ren, Liu, Lu, Matsuura, Manabu, Lambowitz, Alan M., Perlman, Philip S.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60849/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11687644/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.231494498
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