Comparison of two different methods of image analysis for the assessment of microglial activation in patients with multiple sclerosis using (R)-[N-methyl-carbon-11]PK11195

Chronic active multiple sclerosis (MS) lesions have a rim of activated microglia/macrophages (m/M) leading to ongoing tissue damage, and thus represent a potential treatment target. Activation of this innate immune response in MS has been visualized and quantified using PET imaging with [(11)C]-(R)-...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Kang, Yeona, Schlyer, David, Kaunzner, Ulrike W., Kuceyeski, Amy, Kothari, Paresh J., Gauthier, Susan A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084893/
https://ncbi.nlm.nih.gov/pubmed/30091993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201289
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