(11)C‐PK11195 PET–based molecular study of microglia activation in SOD1 amyotrophic lateral sclerosis

OBJECTIVE: Neuroinflammation is considered a key driver for neurodegeneration in several neurological diseases, including amyotrophic lateral sclerosis (ALS). SOD1 mutations cause about 20% of familial ALS, and related pathology might generate microglial activation triggering neurodegeneration. (11)...

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Veröffentlicht in:Ann Clin Transl Neurol
Hauptverfasser: Tondo, Giacomo, Iaccarino, Leonardo, Cerami, Chiara, Vanoli, Giovanna Emilia, Presotto, Luca, Masiello, Valeria, Coliva, Angela, Salvi, Fabrizio, Bartolomei, Ilaria, Mosca, Lorena, Lunetta, Christian, Perani, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480909/
https://ncbi.nlm.nih.gov/pubmed/32762033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51112
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