Interneurons secrete prosaposin, a neurotrophic factor, to attenuate kainic acid-induced neurotoxicity

Prosaposin (PS) is a secretory neurotrophic factor, as well as a regulator of lysosomal enzymes. We previously reported the up-regulation of PS and the possibility of its axonal transport by GABAergic interneurons after exocitotoxicity induced by kainic acid (KA), a glutamate analog. In the present...

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Publicat a:IBRO Rep
Autors principals: Nabeka, Hiroaki, Saito, Shouichiro, Li, Xuan, Shimokawa, Tetsuya, Khan, Md. Sakirul Islam, Yamamiya, Kimiko, Kawabe, Soichiro, Doihara, Takuya, Hamada, Fumihiko, Kobayashi, Naoto, Matsuda, Seiji
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084830/
https://ncbi.nlm.nih.gov/pubmed/30135939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibror.2017.07.001
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