Prosaposin Overexpression following Kainic Acid-Induced Neurotoxicity

Because excessive glutamate release is believed to play a pivotal role in numerous neuropathological disorders, such as ischemia or seizure, we aimed to investigate whether intrinsic prosaposin (PS), a neuroprotective factor when supplied exogenously in vivo or in vitro, is up-regulated after the ex...

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Veröffentlicht in:PLoS One
Hauptverfasser: Nabeka, Hiroaki, Uematsu, Keigo, Takechi, Hiroko, Shimokawa, Tetsuya, Yamamiya, Kimiko, Li, Cheng, Doihara, Takuya, Saito, Shouichiro, Kobayashi, Naoto, Matsuda, Seiji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251898/
https://ncbi.nlm.nih.gov/pubmed/25461957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110534
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