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A Prosaposin-Derived Peptide Alleviates Kainic Acid-Induced Brain Injury
Four sphingolipid activator proteins (i.e., saposins A–D) are synthesized from a single precursor protein, prosaposin (PS), which exerts exogenous neurotrophic effects in vivo and in vitro. Kainic acid (KA) injection in rodents is a good model in which to study neurotrophic factor elevation; PS and...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4436272/ https://ncbi.nlm.nih.gov/pubmed/25993033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126856 |
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