A Prosaposin-Derived Peptide Alleviates Kainic Acid-Induced Brain Injury

Four sphingolipid activator proteins (i.e., saposins A–D) are synthesized from a single precursor protein, prosaposin (PS), which exerts exogenous neurotrophic effects in vivo and in vitro. Kainic acid (KA) injection in rodents is a good model in which to study neurotrophic factor elevation; PS and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nabeka, Hiroaki, Shimokawa, Tetsuya, Doihara, Takuya, Saito, Shouichiro, Wakisaka, Hiroyuki, Hamada, Fumihiko, Kobayashi, Naoto, Matsuda, Seiji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436272/
https://ncbi.nlm.nih.gov/pubmed/25993033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126856
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