RNA sequencing reveals upregulation of a transcriptomic program associated with stemness in metastatic prostate cancer cells selected for taxane resistance

Patients with metastatic castration-resistant prostate cancer (mCRPC) develop resistance to conventional therapies including docetaxel (DTX). Identifying molecular pathways underlying DTX resistance is critical for developing novel combinatorial therapies to prevent or reverse this resistance. To id...

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Udgivet i:Oncotarget
Main Authors: Cajigas-Du Ross, Christina K., Martinez, Shannalee R., Woods-Burnham, Leanne, Durán, Alfonso M., Roy, Sourav, Basu, Anamika, Ramirez, Joshua A., Ortiz-Hernández, Greisha L., Ríos-Colón, Leslimar, Chirshev, Evgeny, Sanchez-Hernandez, Evelyn S., Soto, Ubaldo, Greco, Celine, Boucheix, Claude, Chen, Xin, Unternaehrer, Juli, Wang, Charles, Casiano, Carlos A.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084384/
https://ncbi.nlm.nih.gov/pubmed/30100995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25744
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