Specificity of Antinuclear Autoantibodies Recognizing the Dense Fine Speckled Nuclear Pattern: Preferential Targeting of DFS70/LEDGFp75 Over its Interacting Partner MeCP2

Human antinuclear autoantibodies (ANAs) targeting the dense fine speckled (DFS) nuclear protein DFS70, commonly known as lens epithelium derived growth factor p75 (LEDGFp75), present a clinical puzzle since their significance remains elusive. While their frequencies are low in ANA-positive autoimmun...

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Détails bibliographiques
Publié dans:Clin Immunol
Auteurs principaux: Basu, Anamika, Woods-Burnham, Leanne, Ortiz, Greisha, Rios-Colon, Leslimar, Figueroa, Johnny, Albesa, Roger, Andrade, Luis E., Mahler, Michael, Casiano, Carlos A.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712632/
https://ncbi.nlm.nih.gov/pubmed/26235378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2015.07.014
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