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An insight into tetrahydro-β-carboline–tetrazole hybrids: synthesis and bioevaluation as potent antileishmanial agents
A series of 2,3,4,9-tetrahydro-β-carboline tetrazole derivatives (14a–u) have been synthesized utilizing the Ugi multicomponent reaction and were identified as potential antileishmanial chemotypes. Most of the screened derivatives exhibited significant in vitro activity against the promastigote (IC(...
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| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6084189/ https://ncbi.nlm.nih.gov/pubmed/30108893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00125h |
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