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Site-specific structural order in Alzheimer's Aβ42 fibrils

Deposition of amyloid fibrils is a pathological hallmark of Alzheimer's disease. Aβ42 is the major protein whose aggregation leads to the formation of these fibrils. Understanding the detailed structure of Aβ42 fibrils is of particular importance for delineating the mechanism of Aβ42 aggregatio...

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Publicat a:R Soc Open Sci
Autors principals: Wang, Hongsu, Lee, Yoon Kyung, Xue, Christine, Guo, Zhefeng
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society Publishing 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083707/
https://ncbi.nlm.nih.gov/pubmed/30109072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.180166
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