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Sirolimus-Induced Hepatitis in Two Patients with Hyperinsulinemic Hypoglycemia

Sirolimus has been reported to be effective in the treatment of the diffuse form of congenital hyperinsulinism (CHI), unresponsive to diazoxide and octreotide, without causing severe side effects. Two newborns with CHI due to homozygous ABCC8 gene mutations were started on sirolimus aged 21 and 17 d...

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Podrobná bibliografie
Vydáno v:J Clin Res Pediatr Endocrinol
Hlavní autoři: Haliloğlu, Belma, Tüzün, Heybet, Flanagan, Sarah E., Çelik, Muhittin, Kaya, Avni, Ellard, Sian, Özbek, Mehmet Nuri
Médium: Artigo
Jazyk:Inglês
Vydáno: Galenos Publishing 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083472/
https://ncbi.nlm.nih.gov/pubmed/29217498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/jcrpe.5335
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