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Sirolimus-Induced Hepatitis in Two Patients with Hyperinsulinemic Hypoglycemia

Sirolimus has been reported to be effective in the treatment of the diffuse form of congenital hyperinsulinism (CHI), unresponsive to diazoxide and octreotide, without causing severe side effects. Two newborns with CHI due to homozygous ABCC8 gene mutations were started on sirolimus aged 21 and 17 d...

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Detalhes bibliográficos
Publicado no:J Clin Res Pediatr Endocrinol
Main Authors: Haliloğlu, Belma, Tüzün, Heybet, Flanagan, Sarah E., Çelik, Muhittin, Kaya, Avni, Ellard, Sian, Özbek, Mehmet Nuri
Formato: Artigo
Idioma:Inglês
Publicado em: Galenos Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083472/
https://ncbi.nlm.nih.gov/pubmed/29217498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/jcrpe.5335
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