Arylpyrrole and fipronil analogues that inhibit the motility and/or development of Haemonchus contortus in vitro

Due to widespread drug resistance in parasitic nematodes, there is a need to develop new anthelmintics. Given the cost and time involved in developing a new drug, the repurposing of known chemicals can be a promising, alternative approach. In this context, we tested a library (n = 600) of natural pr...

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Publicat a:Int J Parasitol Drugs Drug Resist
Autors principals: Dilrukshi Herath, H.M.P., Song, Hongjian, Preston, Sarah, Jabbar, Abdul, Wang, Tao, McGee, Sean L., Hofmann, Andreas, Garcia-Bustos, Jose, Chang, Bill C.H., Koehler, Anson V., Liu, Yuxiu, Ma, Qiaoqiao, Zhang, Pengxiang, Zhao, Qiqi, Wang, Qingmin, Gasser, Robin B.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Regular article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083343/
https://ncbi.nlm.nih.gov/pubmed/30081296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2018.06.002
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