Tetrahydroquinoxalines induce a lethal evisceration phenotype in Haemonchus contortus in vitro

In the present study, the anthelmintic activity of a human tyrosine kinase inhibitor, AG-1295, and 14 related tetrahydroquinoxaline analogues against Haemonchus contortus was explored. These compounds were screened against parasitic larvae - exsheathed third-stage (xL3) and fourth-stage (L4) - using...

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Publicat a:Int J Parasitol Drugs Drug Resist
Autors principals: Jiao, Yaqing, Preston, Sarah, Garcia-Bustos, Jose F., Baell, Jonathan B., Ventura, Sabatino, Le, Thuy, McNamara, Nicole, Nguyen, Nghi, Botteon, Antony, Skinner, Cameron, Danne, Jill, Ellis, Sarah, Koehler, Anson V., Wang, Tao, Chang, Bill C.H., Hofmann, Andreas, Jabbar, Abdul, Gasser, Robin B.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357688/
https://ncbi.nlm.nih.gov/pubmed/30690282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2018.12.007
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