Synthetic Kavalactone Analogues with Increased Potency and Selective Anthelmintic Activity against Larvae of Haemonchus contortus In Vitro

Kava extract, an aqueous rhizome emulsion of the plant Piper methysticum, has been used for centuries by Pacific Islanders as a ceremonial beverage, and has been sold as an anxiolytic agent for some decades. Kavalactones are a major constituent of kava extract. In a previous investigation, we had id...

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Publicado en:Molecules
Autores principales: Herath, H.M.P. Dilrukshi, Taki, Aya C., Nguyen, Nghi, Garcia-Bustos, José, Hofmann, Andreas, Wang, Tao, Ma, Guangxu, Chang, Bill C.H., Jabbar, Abdul, Sleebs, Brad E., Gasser, Robin B.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221733/
https://ncbi.nlm.nih.gov/pubmed/32344703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25082004
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