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BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity
Base editor (BE), containing a cytidine deaminase and catalytically defective Cas9, has been widely used to perform base editing. However, the narrow editing window of BE limits its utility. Here, we developed a new editing technology named as base editor for programming larger C to U (T) scope (BE-...
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| Publicat a: | Cell Res |
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| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6082914/ https://ncbi.nlm.nih.gov/pubmed/29875396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0052-4 |
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