SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation

Regulatory T (Treg) cells are essential for maintaining immune homeostasis and tolerance, but the mechanisms regulating the stability and function of Treg cells have not been fully elucidated. Here we show SUMO-specific protease 3 (SENP3) is a pivotal regulator of Treg cells that functions by contro...

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Publicado no:Nat Commun
Main Authors: Yu, Xiaoyan, Lao, Yimin, Teng, Xiao-Lu, Li, Song, Zhou, Yan, Wang, Feixiang, Guo, Xinwei, Deng, Siyu, Chang, Yuzhou, Wu, Xuefeng, Liu, Zhiduo, Chen, Lei, Lu, Li-Ming, Cheng, Jinke, Li, Bin, Su, Bing, Jiang, Jin, Li, Hua-Bing, Huang, Chuanxin, Yi, Jing, Zou, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082899/
https://ncbi.nlm.nih.gov/pubmed/30089837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05676-6
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