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Kisspeptin/GPR54 signaling restricts antiviral innate immune response through regulating calcineurin phosphatase activity
G protein–coupled receptor 54 (GPR54), the key receptor for the neuropeptide hormone kisspeptin, plays essential roles in regulating puberty development and cancer metastasis. However, its role in the antiviral innate immune response is unknown. We report that virus-induced type I interferon (IFN-I)...
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| Publicado no: | Sci Adv |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6082648/ https://ncbi.nlm.nih.gov/pubmed/30101190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aas9784 |
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